Bone mineral density (BMD) at the femoral neck, trochanter, spine, radius, and total body, and soft-tissue composition were taken at baseline, 0.5 years, and two years. After two years, both groups lost BMD at the femoral neck and trochanter , whereas only the WL-M group reduced BMD at the 1/3 radius. There was greater BMD loss at the trochanter and 1/3 radius in the WL-M group compared with the WL-R group after two years.
The study concluded that, after two years, there is no recovery of bone loss induced by weight reduction, irrespective of weight regain. Weight regain does not result in recovery of bone, but it prevents greater loss at the trochanter and 1/3 radius compared with reduced-obese women. These data suggest that the period after weight loss may be an important point in time to prevent bone loss for those who maintain weight and those who regain weight.
This information is taken from a much longer article, Does Bone Loss Begin After Weight Loss Ends?