Skeleton Pirate

Skeleton Pirate
Artist: LindaB

WELCOME TO STRONTIUM FOR BONES BLOG

Have you experienced, or read about, negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), and other bisphosphonates prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.

Browse the posts and visit the link library of references.

Visit me at www.twitter.com






Blog Archive

Tuesday, April 23, 2013

Strontium and Your Heart


A committee of the European Medicines Agency (EMA) has recommended the following restrictions in the use of strontium ranelate (sold in the European Union under the brand names Protelos and Osseor) to reduce the risk of adverse cardiac events:

1a. Strontium ranelate should only be used for the treatment of severe osteoporosis in postmenopausal women at high risk for fracture and severe osteoporosis in men at increased risk for fracture.

2a.Strontium ranelate should not be used in patients with current or past history of ischemic heart disease (such as angina or MI), peripheral arterial disease (PAD), or cerebrovascular disease.

3a.Strontium ranelate should not be used in patients with hypertension that is not controlled by treatment.


What, if anything, should those of us taking strontium citrate do?

Here is what I think.

1b. Strontium citrate can be used as a supplement by men and women with osteopenia or osteoporosis. (I believe the first restriction on strontium ranelate is mostly for cost containment because bisphosphonates, especially the generic equivalents, are much cheaper than strontium ranelate.) 

2b. Strontium citrate can be used UNDER MEDICAL SUPERVISION in patients with current or past history of ischemic heart disease, PAD, or cerebrovascular disease.

    3b. Strontium citrate should not be used in patients with uncontrolled hypertension. Patients must get their hypertension under control by medication. Strontium citrate can be used UNDER MEDICAL SUPERVISION in patients with hypertension that is controlled by treatment.

4 comments:

Kathy said...

Thanks for keeping us posted! Looks like they might release some more information (hopefully some actual numbers) at the end of their big meeting on Thursday!

Kath

Anonymous said...

Exactly what medical qualifications or expertise do you have that allows you to make such recommendations that go against these official recommendations? Especially your 2b!

BoneLady said...

To: Anonymous of 04/23/2013,

The recommendations of the EMA committee are for the use of strontium ranelate (a prescription drug) in the European Union. They do NOT pertain to the use of strontium citrate (a supplement) sold in the United States and Canada.

The negative side effects of strontium ranelate MAY or MAY NOT pertain to strontium citrate. Therefore, I have provided my opinions on each of the three recommendations for persons using strontium citrate. I wrote, “What, if anything, should those of us taking strontium citrate do? Here is what I think.”

I stand by all three points, including 2b: “Strontium citrate can be used UNDER MEDICAL SUPERVISION in patients with current or past history of ischemic heart disease, PAD, or cerebrovascular disease.”

BoneLady said...

Kathy,

See my update after the meeting, and thanks for reading and commenting.

Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone
Source: www.mayoclinic.com

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.