Strontium is safe for most people, but there are certain individuals who should not take it. These include those with any of the following disorders:
- Decreased kidney function.
- History of blood clots in the veins (venous thromboembolism, e.g., deep vein thrombosis or pulmonary embolism).
- Blood disorders that increase the risk of blood clots in the veins, e.g. antiphospholipid syndrome, factor V Leiden.
There is some evidence that strontium could slightly increase the incidence of blood clots. The tests were performed on strontium ranelate.
Strontium should also not be taken by children nor by pregnant or lactating women.
Skeleton Pirate
Artist: LindaB
WELCOME TO STRONTIUM FOR BONES BLOG
Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Friday, April 17, 2009
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Wandering Skeleton
Artist: Joel Hoekstra
Osteoporotic Bone
Source: www.mayoclinic.com
How Strontium Builds Bones
Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
For More Information about Strontium
- A Dose-response Study With Strontium Malonate
- A Review of the latest insights into the mechanism of action of strontium in bone
- Antifracture Efficacy Over 10 Years With Strontium Ranelate
- Combination of Micronutrients for Bone (COMB) Study: Bone Density after Micronutrient Intervention
- Echolight REMS Scan of Young, Normal Female
- Effect of bone strontium on BMD measurements
- Effect of Lumbar Scoliosis on DXA Results
- Effects of SrR on Calcium Metabolism
- Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection
- Influence of strontium on bone mineral density and bone mineral content measurements by dual X-ray absorptiometry
- Interpretation of BMD Scans in Patients Stopping Strontium
- Melatonin-micronutrients Osteopenia Treatment Study (MOTS)
- National Osteoporosis Foundation
- Osteoporosis And Bone Physiology
- Post-Marketing Assessment of the Safety of Strontium Ranelate
- PubMed Abstract On The SOTI Study
- PubMed Abstract On The TROPOS Study
- Strontium ranelate Aristo
- Strontium Ranelate For Spinal Osteoarthritis
- Strontium: Breakthrough Against Osteoporosis
- Summary Safety Review - Strontium
- The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment
- Thirteen Key Diagnostic Tests
2 comments:
The brochure I got with my strontium ralenate says that only people with severely decreased kidney function need to be concerned about strontium for bones.
Moderately decreased kidney function should not be a problem. The safe creatinine clearance level is specified in the brochure to assist your doctor to determine whether or not you will be at risk.
From what I could see, I was not convinced that any of the other adverse effects are real. I think they are just statistical artifacts.
I still have two months supply of Fosamax that I will use up and then I will switch to strontium.
In my opinion, people are focusing on the wrong problem. They should be concerned about how to get enough vitamin D and the formulation of their calcium supplement.
Vitamin D2 is a waste of money, while D3 is not easy to find in formulations that do not also contain megadoses of vitamin A. The risk of taking too much vitamin A far outweighs any risk from taking too much strontium.
Calcium carbonate may be a waste of money too, if the acidity of your stomach is low. Better to take a compound that is more readily available and to make sure the formulation has the other essential ingredients for bone health: magnesium, manganese and zinc.
To Anonymous post of 5/12/09:
Thank you for your comments. I hope you will keep us posted on your progress after being on strontium ranelate for a while.
I agree with you that the possible connection between strontium and blood clots is not strong.
My vitamin D supplementation is with D3, however there is some new evidence that D2 may be just as good. Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status. A summary of the article is available at http://www.sciencedaily.com/releases/2008/01/080102122306.htm.
I'm sure there are other researchers who have found just the opposite.
Good luck to you.
BoneLady
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