Skeleton Pirate

Skeleton Pirate
Artist: LindaB


Have you experienced, or read about, negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), and other bisphosphonates prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

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Friday, April 17, 2009

Strontium Safety

Strontium is safe for most people, but there are certain individuals who should not take it. These include those with any of the following disorders:

- Decreased kidney function.

- History of blood clots in the veins (venous thromboembolism, e.g., deep vein thrombosis or pulmonary embolism).

- Blood disorders that increase the risk of blood clots in the veins, e.g. antiphospholipid syndrome, factor V Leiden.

There is some evidence that strontium could slightly increase the incidence of blood clots. The tests were performed on strontium ranelate.

Strontium should also not be taken by children nor by pregnant or lactating women.


Anonymous said...

The brochure I got with my strontium ralenate says that only people with severely decreased kidney function need to be concerned about strontium for bones.

Moderately decreased kidney function should not be a problem. The safe creatinine clearance level is specified in the brochure to assist your doctor to determine whether or not you will be at risk.

From what I could see, I was not convinced that any of the other adverse effects are real. I think they are just statistical artifacts.

I still have two months supply of Fosamax that I will use up and then I will switch to strontium.

In my opinion, people are focusing on the wrong problem. They should be concerned about how to get enough vitamin D and the formulation of their calcium supplement.

Vitamin D2 is a waste of money, while D3 is not easy to find in formulations that do not also contain megadoses of vitamin A. The risk of taking too much vitamin A far outweighs any risk from taking too much strontium.

Calcium carbonate may be a waste of money too, if the acidity of your stomach is low. Better to take a compound that is more readily available and to make sure the formulation has the other essential ingredients for bone health: magnesium, manganese and zinc.

BoneLady said...

To Anonymous post of 5/12/09:

Thank you for your comments. I hope you will keep us posted on your progress after being on strontium ranelate for a while.

I agree with you that the possible connection between strontium and blood clots is not strong.

My vitamin D supplementation is with D3, however there is some new evidence that D2 may be just as good. Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status. A summary of the article is available at

I'm sure there are other researchers who have found just the opposite.

Good luck to you.


Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.