Skeleton Pirate

Skeleton Pirate
Artist: LindaB


Have you experienced, or read about, negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), and other bisphosphonates prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

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Monday, April 17, 2017

Strontium Ranelate Withdrawal from European Countries

Cessation of marketing of Protelos/Osseor: Extract of the letter sent to European Medicine Agency (EMA) and national European Agencies on 10 February 2017


Similar letters, adapted to local regulations, have been sent to all countries worldwide where Protelos/Osseor® is marketed

PROTELOS/OSSEOR® - Cessation of marketing

On 21 September 2004, Protelos/Osseor® (strontium ranelate), centrally authorised medicinal product, was granted a Marketing Authorisation by the European Commission for the European Union (EU).

Protelos/Osseor® is indicated in the treatment of severe osteoporosis in postmenopausal women and in adult men at high risk of fracture, for whom treatment with other medicinal products approved for the treatment of osteoporosis is not possible due to, for example, contraindications or intolerance.

Les Laboratoires Servier hereby notify the cease of the marketing, permanently, in the European countries where it is currently marketed.
This worldwide and strategic decision is taken for commercial reasons based on the following grounds:
  • The restricted indication/limited use of Protelos/Osseor®,
  • The continuous decrease of patients treated with Protelos/Osseor®.
Les Laboratoires Servier will cease the distribution of Protelos/Osseor® in August 2017.
Servier, founded in 1954, is the first independent pharmaceutical group. We are present in 140 countries, with more than 21 000 employees, including close to 3000 in R&D.

My note: Those who will no longer be prescribed strontium ranelate can buy nonprescription strontium citrate. 


Eliot W. Collins said...

Wasn't there also a concern with the cardiovascular risk associated with long term use of strontium ranelate?

BoneLady said...

To: Eliot W. Collins,

Yes, there was an increased risk of nonfatal heart attacks in people with a history of cardiac problems. That finding precipitated the limitations placed on prescribing SR. The decrease in prescriptions caused Servier to stop marketing SR in Europe.

BirdBones said...

Hi BoneLady. I just ordered the strontium that you recommended. I am only 51. I have pretty severe OP in my spine. Can you email me and we possibly talk? I am Carol in Phoenix, AZ. is my email.

BoneLady said...

Hi! BirdBones/Carol,

You can ask me anything you want via this blog, and I will answer you. Others may be interested in reading your questions and comments and my replies.

I hope the strontium citrate works well for your osteoporosis of the spine.

Best wishes,


Anonymous said...

Have you noted that a study of curcumin (turmeric) combined with soy lecithin has positively impacted bone development? I first noticed a British news article at A more detailed version of the study seems to be located at . It is of note that plain turmeric is not effective as there is little bioavailability. Combining with soy lecithin appears to allow much greater bioavailability. The version utilized in this study was Meriva. I'd be interested in your thoughts.

Anonymous said...

Hi BoneLady,

Since I'm new to your site, would you please tell me how your bone density is doing these days in 2017?? I'm considering taking strontium citrate but want to hear more about a real-life success story first.

Thanks in advance,

BoneLady said...

Hi Kathy,

My latest results were posted on my blog on August 4, 2016. The following URL will take you to that post, which shows my bone density is in the upper range of osteopenia.

BoneLady said...

To Anonymous Poster of 9/22/17:

The study you referred to is a small (57 subjects), short (24 weeks), preliminary study on Thorne Research Meriva,a curcumin with soy. Thorne now has a soy-free Meriva.
It's too early to reach conclusions about curcumin to prevent and manage osteopenia, but curcumin is an anti-inflammatory compound with many uses.

Jane B. said...

I just stumbled across the incidence of serious cardiovascular events with the use of the bisphosphonate alendronate: it's a staggering 1.9%, compared with the 1.6% that vilified strontium ranelate.

Strontium citrate continues to be a great choice.

BoneLady said...

Jane B.

Thanks for the link. I agree that strontium citrate continues to be a great choice. I've been on a full dose (680 mg strontium/day) for nearly 10 years with no problems associated with it.

Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.