Most of my posts are about my own experience with strontium citrate and about research on the various strontium salts. This post is about Sara S. DeHart's strontium success story, which she wrote about herself in two articles, the most recent one published online just a few days ago. In 2006, she was taking Actonel and developed a fracture at T-9. Later, that same year, she switched to strontium citrate (750 mg strontium/day) and has had no further vertebral fractures. Here are her T-scores from 2006 to the present:
Left Hip Lumbar Spine
2006 -1.2 -1.4
2008 -0.6 -0.2
2010 -0.5 +0.2
Here is the original article: http://onlinejournal.com/artman/publish/printer_6185.shtml
Skeleton Pirate
Artist: LindaB
WELCOME TO STRONTIUM FOR BONES BLOG
Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.
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Browse the posts and visit the link library of references.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Tuesday, August 10, 2010
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Wandering Skeleton
Artist: Joel Hoekstra
Osteoporotic Bone
Source: www.mayoclinic.com
How Strontium Builds Bones
Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
For More Information about Strontium
- A Dose-response Study With Strontium Malonate
- A Review of the latest insights into the mechanism of action of strontium in bone
- Antifracture Efficacy Over 10 Years With Strontium Ranelate
- Combination of Micronutrients for Bone (COMB) Study: Bone Density after Micronutrient Intervention
- Echolight REMS Scan of Young, Normal Female
- Effect of bone strontium on BMD measurements
- Effect of Lumbar Scoliosis on DXA Results
- Effects of SrR on Calcium Metabolism
- Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection
- Influence of strontium on bone mineral density and bone mineral content measurements by dual X-ray absorptiometry
- Interpretation of BMD Scans in Patients Stopping Strontium
- Melatonin-micronutrients Osteopenia Treatment Study (MOTS)
- National Osteoporosis Foundation
- Osteoporosis And Bone Physiology
- Post-Marketing Assessment of the Safety of Strontium Ranelate
- PubMed Abstract On The SOTI Study
- PubMed Abstract On The TROPOS Study
- Strontium ranelate Aristo
- Strontium Ranelate For Spinal Osteoarthritis
- Strontium: Breakthrough Against Osteoporosis
- Summary Safety Review - Strontium
- The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment
- Thirteen Key Diagnostic Tests
7 comments:
One question I have, does Strontium Carbonate work as well as Strontium Citrate? The company from which I ordered my Strontium uses the carbonate. I didn't notice that when I ordered it and now have 90 days supply of it.
From what I can see on the Web, they seem to both be about the same. But, I thought I'd check with you about it to ensure that is correct.
Thank you in advance
S. Lee Tignor
To: S. Lee Tignor
Per Dr. Hoffman, “strontium is available as strontium carbonate, strontium chloride, strontium sulfate, strontium gluconate and strontium citrate. In clinical research strontium gluconate was absorbed better than strontium carbonate. It is my clinical opinion that strontium citrate is absorbed better than the other forms of this mineral.” Source: http://www.drhoffman.com/page.cfm/447
Like Dr. Hoffman, I also believe that strontium carbonate is not the best source. Strontium citrate is more readily absorbed than strontium carbonate, just as calcium citrate is more readily absorbed than calcium carbonate. If you eat food when you take calcium carbonate, you can get around the absorption problem, but you would not want to eat food containing calcium and take a strontium product because calcium and strontium compete for absorption.
This does not mean that you will not benefit from the strontium carbonate. However, the more readily absorbable the strontium salt is, the more elemental strontium your body will be able to utilize.
To: S. Lee Tignor
Take your strontium carbonate with lemonade or orange juice. The acid will help absorption.
When you have completed the 90-day supply of strontium carbonate, switch to strontium citrate. I take Doctor's Best Strontium Bone Maker, which I buy from www.iherb.com.
Good luck to you.
BeckySue asks:
Wouldn't it be better to take strontium in 2 doses spread throughout the day as long as it was a few hours from the calcium doses? That is how they instruct calcium to be taken. Also, is the optimal does 680 mg of strontium citrate or strontium the element? And who came up with this optimal dose. Thanks for all your work and publishing on this. I really appreciate it.
BeckySue,
The optimal dose to treat osteoporosis is 680 mg elemental strontium derived from roughly two grams of the strontium salt (e.g., strontium ranelate, strontium citrate). Half that dose appears optimal for preventing osteoporosis in postmenopausal women.
Multiple clinical studies utilizing different forms of strontium for promoting healthy bones have been conducted since the 1950s. However, most of the large clinical trials on strontium for osteoporosis have been conducted by or for Servier, the French company that manufactures strontium ranelate. Many of the studies, including dosing studies, were done by J.Y. Reginster et al. The company's directions for taking strontium ranelate are to take the 2 grams (680 mg elemental strontium) at one time 3-4 hours away from food and calcium supplements.
Maybe the only reason for taking it all at one time is that strontium ranelate is sold as a powder that one must dissolve in water. Perhaps, the researchers felt it would be easier for most people to take it all at one time, or easier to separate the strontium from calcium this way. I don't think it would hurt to take strontium citrate in two doses, if that is your preference.
I hope I have answered your questions satisfactorily. Good luck to you.
I have tried strontrium ranelate (Protos 2g) in the powder form dissolved with water and found the side effects unbearable after two months (headaches, unexplained aches and pains, bloating, swelling). Does anyone have experiences with stroniutm carbonate or citrate and the side effects of the tablet form? Does anyone have tips for reducing these side effects?
Yascar,
I have taken strontium citrate for four years with virtually no side effects. I did experience some constipation at first, but, since increasing my fiber consumption, I have not had that problem.
Some of the negative side effects from strontium ranelate are due to ranelic acid and/or aspartame and other synthetic sweeteners used in the powder. If you experienced "headaches, unexplained aches and pains, bloating, swelling" after two months on strontium ranelate,you should not take this preparation.
You could try strontium citrate and see how that works for you. Strontium citrate is more readily absorbed than strontium carbonate. Let me know what you decide and how you are doing.
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