Skeleton Pirate

Skeleton Pirate
Artist: LindaB

WELCOME TO STRONTIUM FOR BONES BLOG

Have you experienced, or read about, negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), and other bisphosphonates prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

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Thursday, May 28, 2009

Update On Strontium Malonate For Osteoporosis

Osteologix, Inc. has received a key U.S. Patent Allowance for its osteoporosis drug, NB S101 (strontium malonate). This brings the company closer to its goal of manufacturing and marketing a prescription strontium drug in the U.S.

The Notice of Allowance from the U.S. Patent and Trademark Office is for U.S. Patent Application Number 11/269,289 titled "Water-Soluble Strontium Salts for Use in Treatment of Cartilage and/or Bone Conditions." It allows claims covering the treatment of osteoporosis and related bone conditions using NB S101 (strontium malonate). The patent will most likely issue in the second half of 2009 and expire in 2024.

The company has a number of other pending patent applications covering various aspects of the NB S101 drug program, including composition, manufacturing and method of use patent applications. "Based on the Notice of Allowance and the claims allowed by the USPTO, we believe the intellectual property protections established by this US patent allowance, coupled with our recently upheld European equivalent, will significantly enhance our ability to finalize strong development collaborations with potential partners to complete the Phase III development of NB S101 in osteoporosis," stated Philip J. Young, President and Chief Executive Officer of Osteologix. This is from the company's website at http://www.osteologix.com/.

10 comments:

Sherry said...

Hi - I'm glad to find your site. Are you familiar with a strontium product called Ulitimate Bone Support? It comes from a company called Advanced Bionutritionals and is promoted by direct mail from a Dr. Nan Fuchs. After doing research on strontium - including your well done site - I'm tempted to try the formula but I'd first like to know if you or one of your readers is familiar with it. If you'd like, I can email you the formula components.

BoneLady said...

Hi!Sherry, I had not heard of Ultimate Bone Support until now, but I checked out Advanced Bionutritionals' website and found the formula components. It contains several ingredients,not just strontium. One dose contains only 250 mg strontium. The optimal daily dose is 680 mg elemental strontium.

BoneLady

Berle said...
This comment has been removed by the author.
BoneLady said...

Hi!Berle,

I'm glad you like my blog, but I have no idea what you are talking about. If I had a 75% improvement from taking strontium citrate, or any other product, I'd probably break a bone from all the jumping up and down I'd be doing!

I've only had one DEXA scan,the one that diagnosed my osteoporosis. Those results are posted on my blog. I am scheduled for my second scan July 6, 2009. I'll know how well the strontium citrate is working when I get the results. Keep checking back because I will post the results on my blog.

BoneLady

Berle said...
This comment has been removed by the author.
BoneLady said...

Hi!Berle, Although you did not ask your question under my post, "Poll Results On T-Scores After Strontium Citrate,"you must be referring to that poll, which asked, "Did your DEXA scan T-scores improve after taking strontium citrate? Twelve people (75%)answered YES and 4 (25%) said NO.

The poll did not ask whether the scores were corrected or uncorrected, so I cannot say for sure whether they were or not. But let me make an educated guess, and I would have to say they were uncorrected. The reason is that in the U.S. we do not have a prescription form of strontium available. Therefore, most radiologists will not correct T-scores for strontium as they would in countries where strontium ranelate is available.

Of course, patients can correct their own scores by 10% or more, but the exact correction for over-the-counter strontium supplements is not known. Servier, the manufacturer of Protelos (strontium ranelate) says it is not necessary to correct each score because any improvement correlates with a lower risk of fractures.

Anonymous said...

Hi there - I have my script for Strontium Ranelate, there it sits, where it has been for the last 2.5 years looking at me. Why?he dsrn stuff is buffered wirth Aspartame! I refuse to take Aspartame or ANY artificial sweetener. One is sooooo fed up of the French drug cos. buffering their meds with sweeteners. Either it is sweeeteners, or Thimerasol or Aluminium or even mixes of, let alone other ghastly carriers and buffers. Sigh.

I take Strontium Citrate which is the SAME as strontium Ranelate, Strontium Manelate etc etc. Excepting, that Strontium Citrate IS the natural form whereas the other Stronitums (raanelate and manelate) is the chemical engineered form of the Citratte.

I buy S'Citrate over the counter. C'est tres facile.

Mystral - France

Lisa said...

Hi,
I am The assistant editor with disease.com. I really liked your site and I am interested in building a relationship with your site. We want to spread public awareness. I hope you can help me out. Your site is a very useful resource.

Please email me back with your URL in subject line to take a step ahead an to avoid spam.

Thank you,
Lisa Hope
lisa.disease.com@gmail.com

jimiji said...

Hi, I am a 65 yrold male taking Strontium Bone Maker fro 'Doctors Best'.
my Endocrinologist says i have 8 to 15 % bone growth and from high risk to moderate/moderate to Penic in the two primary arreas. 680 mg dose. im not regular with it. Maybe 3 or 4 pills a week or the results would be better. However my GFR/Kidney and Creatinine are coming up remarkable and im getting Osteo nodules on my lateral epicondyles. very painful. Is the Strontium causing it or should i get worked up by Rheumatologist?!thanks, jimeaglesmith@gmail.com as i may not find this page again>

BoneLady said...

jimiji,

Strontium is not recommended for patients with severe renal impairment (creatinine clearance below 30 ml/min). No dose adjustment is required in patients with mild-to-moderate renal impairment (30-70 ml/min creatinine clearance).

In clinical trials, strontium has never been found to cause osteo nodules on the outer part of the elbow (the lateral epicondyle) or any other body part. Though commonly known as tennis elbow, lateral epicondylitis may be caused by various sports and occupational activities.

Congratulations on your progress with strontium citrate. You should discuss your test results and concerns with your endocrinologist.

Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone
Source: www.mayoclinic.com

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.