Skeleton Pirate

Skeleton Pirate
Artist: LindaB

WELCOME TO STRONTIUM FOR BONES BLOG

Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

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Friday, July 4, 2014

Monitoring Bone Strontium Intake in Females Taking Strontium Citrate



Ten female volunteers were recruited to have their bone strontium (Sr) levels measured as they self-supplemented with Sr supplements of their choice. Nine of the ten had been diagnosed with osteopenia and/or osteoporosis. Non-invasive bone Sr measurements were performed using an in vivo x-ray fluorescence (IVXRF) I-125 based system. Thirty minute measurements were taken at the finger and ankle, representing primarily cortical and trabecular bone, respectively.

Baseline readings, representing natural bone Sr levels were acquired since all volunteers had no previous intake of Sr based supplements or medications. Once Sr supplements were started, a 24 hour reading was taken, followed by frequent measurements ranging from weekly, biweekly to monthly. The longest volunteer participation was 1535 days (4.2 years).

The mean baseline Sr signal observed for the group was 0.42 ± 0.13 and 0.39 ± 0.07 for the finger and ankle, respectively. After 24 hours, the mean Sr signal rose to 1.43 ± 1.12 and 1.17 ± 0.51, for the finger and ankle, respectively, representing a statistically significant increase. Bone Sr levels continued to increase throughout the length of the study. However, the Sr signal varied widely between the individuals. After three years, the highest Sr signal observed was 28.15 ± 0.86 for the finger and 26.47 ± 1.22 for the ankle in one volunteer compared to 3.15 ± 0.15 and 4.46 ± 0.36, for the finger and ankle, respectively, in another. Furthermore, while it was previously reported by our group, that finger bone Sr levels may plateau within two years, these results suggest otherwise, indicating that bone Sr levels will continue to rise at both bone sites even after 4 years of Sr intake.

The most important points of this study are as follows:
  • The bone Sr signal varies widely between subjects but follows a similar pattern.
  • Results suggest bone Sr levels won't plateau as long as one supplements with Sr.
  • This diagnostic tool is satisfactory for monitoring bone Sr levels over time.
 The original article was published online in “Bone” on February 08, 2014.

http://www.thebonejournal.com/article/S8756-3282%2814%2900004-0/abstract

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Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone
Source: www.mayoclinic.com

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.