Skeleton Pirate

Skeleton Pirate
Artist: LindaB

WELCOME TO STRONTIUM FOR BONES BLOG

Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

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Sunday, January 25, 2015

My DXA Scan Results Look Great After Strontium Citrate



My first DXA scan was in May, 2007 (diagnosed with osteoporosis):

Spine from L1-L4 T-score -3.0
Left hip (total) T-score -2.2
Left femoral neck T-score -2.8

My second DXA scan was in July, 2009 (After 6 months on Fosamax once weekly and 18 months on strontium citrate, 680 mg strontium daily, still at osteoporosis, but scores improved):

Spine (total) T-score -2.7
Left hip (total) T-score -1.7
Left hip (neck) T-score -2.6

My third DXA scan was in August, 2013 (After 5 ½ years on strontium citrate, scan results were at the osteopenia stage; I was probably at the osteopenia stage before this, but I did not have a DXA scan in 2011):

Spine from L1-L4 T-score -1.6
Left hip (total) T-score -1.4
Left hip (neck) T-score -1.4

Osteopenia is defined as T-scores < -1.0 and -2.5.

2 comments:

Unknown said...

Thank you for continuing to post such useful information.
After 4 years of Strontium supplementation, my DXA scan has shown improvement from significantly deteriorating Osteopenia to a Normal scan... I have tried to find information as to making a dose reduction but can find none. I take 227 x 3 at bedtime, 2 - 4 hours away from food/CA supplements. Do you know of a reference to guide me as to a modified regimen? thank you for any assistance.

BoneLady said...

Sharon,

As you can see from my most recent DXA scores, as of August, 2013, I was in the osteopenia stage and getting pretty close to normal. I may be in the normal range by now, and, like you, may soon need to make a decision about whether or not to reduce my dosage. I did not reduce the dosage when my BMD improved from osteoporosis to osteopenia.

From the PREVOS and STRATOS studies, we know the minimum effective doses of strontium ranelate (SR) for treating early postmenopausal non-osteoporotic women and postmenopausal osteoporotic women are 1 gram/day and 2 grams/day, respectively. One gram of strontium ranelate contains about 340 mg elemental strontium, and two grams SR contains about 680 mg strontium.The link to this abstract is on my blog under “For More Information about Strontium.”

http://link.springer.com/article/10.1007%2Fs00198-002-1349-0?LI=true

Your question is what dosage of strontium citrate (SC)should be taken to maintain the normal BMD obtained after four years on 681 mg strontium/ day. This question falls into a gray area. I cannot direct you to a clinical study that answers it. I can only give you my opinion.

After my next DXA scan, if I am in the normal BMD range, I plan to reduce my dosage to 340 mg strontium daily. I believe that is a good maintenance dose because it is the amount recommended for early postmenopausal non-osteoporotic women. I was a postmenopausal osteoporotic woman prior to taking SC.

Since your SC comes in 227-mg capsules, you could drop to one capsule per day.

Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone
Source: www.mayoclinic.com

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.