Sara S. DeHart, MSN, Ph.D., is an 80-year-old woman who was diagnosed with osteopenia at age 63. She was treated initially with Fosamax 10 mg. daily and Estraderm patches twice weekly. She discontinued the patches after about two
years, and Fosamax after about three years. Following a fragility fracture of
the sacrum, she was prescribed Actonel 5 mg five times a week. Her vitamin D
blood level was found to be very low, although she had supplemented with 400 IU vitamin D3 throughout her adult life.
She followed “standards of care” medical
recommendations until she developed a second fragility fracture at T9 while
taking Actonel. At that point, she stopped using Actonel and began taking strontium citrate. She increased her vitamin D3
supplementation. Today, she is 80 years old and her BMD is normal. More
importantly, she has not fractured, even after a recent fall onto an asphalt
driveway! Follow this link to read her amazing story:Skeleton Pirate
WELCOME TO STRONTIUM FOR BONES BLOG
Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Tuesday, October 9, 2012
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Wandering Skeleton
Osteoporotic Bone
How Strontium Builds Bones
Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
For More Information about Strontium
- A Dose-response Study With Strontium Malonate
- A Review of the latest insights into the mechanism of action of strontium in bone
- Antifracture Efficacy Over 10 Years With Strontium Ranelate
- Combination of Micronutrients for Bone (COMB) Study: Bone Density after Micronutrient Intervention
- Echolight REMS Scan of Young, Normal Female
- Effect of bone strontium on BMD measurements
- Effect of Lumbar Scoliosis on DXA Results
- Effects of SrR on Calcium Metabolism
- Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection
- Influence of strontium on bone mineral density and bone mineral content measurements by dual X-ray absorptiometry
- Interpretation of BMD Scans in Patients Stopping Strontium
- Melatonin-micronutrients Osteopenia Treatment Study (MOTS)
- National Osteoporosis Foundation
- Osteoporosis And Bone Physiology
- Post-Marketing Assessment of the Safety of Strontium Ranelate
- PubMed Abstract On The SOTI Study
- PubMed Abstract On The TROPOS Study
- Strontium ranelate Aristo
- Strontium Ranelate For Spinal Osteoarthritis
- Strontium: Breakthrough Against Osteoporosis
- Summary Safety Review - Strontium
- The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment
- Thirteen Key Diagnostic Tests
3 comments:
Do you have an opinion on Whole Body Vibration? WBV
To: Anonymous of 05/09/2013,
My opinion on whole body vibration (WBV) is that the jury is still out about its effectiveness. More studies are needed. I might try it, but only if I were unable to do regular physical exercise. I found both positive and negative information on WBV.
A quote from the Mayo Clinic website states “some research shows that whole body vibration, when performed correctly and under medical supervision when needed, can reduce back pain, improve balance in older adults, and reduce bone loss.” The article includes four references.
http://www.mayoclinic.com/health/whole-body-vibration/AN01598
According to a Reuter’s article (11/14/2011), “Canadian researchers found that of 200 postmenopausal women with low bone mass, those given a whole-body vibration device to use at home for a year showed no clear benefits.”
A comment to the Reuter’s article follows:
“In 2004 Health Canada licensed Dr. Rubin’s Juvent 2000 as a 2nd class medical devise for increasing circulation from the lower extremities to the heart, Increasing or maintaining bone mineral density and increasing lymphatic drainage. Dr. Rubin presented a 25 year study to the International Osteoporosis Society in Toronto in 2004. The results of the controlled study showed an average increase in BMD of 3% and an average increase in muscle mass of 4%.
Further on page 9 of a 25 page report published in 2006 by the office of the Surgeon General US Department of Health & Human Services.
I quote:
For those who cannot ingage in regular physical activity due to disability, mechanical stimulation of the skeleton might prove beneficial. Recent small studies found that use of vibrating platforms increased BMD and slowed bone loss. ( Rubin 2004 et al., Verschueren et al.2004, Ward et al. 2004). This may provide another way to reduce fracture risk both in ederly and in younger individuals with disabling conditions that limit thier ability to exercise. However, the long-term saftey and efficacy of such approaches remain to be determined, and therefore speific rehabilition and exercise programs aimed at increasing activity and function remain critically important in the frail elderly and in younger individuals with neuromusclular dsabilities.
The Toronto Doctor who published her findings has in my opinion been most irresponsible in her testing procedures. This was not a controlled study and therefore in my opinion is less than valid.”
http://www.reuters.com/article/2011/11/14/us-vibration-bonemass-idUSTRE7AD2AO20111114
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