Both the Combination of Micronutrients for Bone (COMB) study and Melatonin-Micronutrients Osteopenia Treatment Study (MOTS) investigated using strontium in conjunction with other supplements. You cannot take strontium without taking sufficient calcium (from food and/or supplements) and vitamin D. You also need magnesium, which was not included in the MOTS protocol, and was provided at a very low dosage in the COMB study.
The COMB study for osteoporosis:
strontium citrate (680 mg)
D3 (2000 IU)
dietary sources of calcium
magnesium (25 mg)
K2 (MK7) (100 mcg)
DHA (250 mg)
daily impact exercises were encouraged.
MOTS for osteopenia:
strontium citrate (450 mg)
D3 (2000 IU)
K2 (MK7) (60 mcg)
melatonin, 5 mg
These ingredients were called MSDK for melatonin, strontium citrate, vitamins D3 and K2.
In addition to study medication, participants were allowed to take less than 1000 IU D3 and less than 1000 mg of calcium. Nearly 87% of the subjects in the MOTS study were taking either calcium/vitamin D3, multivitamins, and/or other dietary supplements.
The BoneLady uses her own protocol for osteoporosis:
strontium citrate (682 mg),
D3 (1300 IU)
calcium (500 mg tablet, about 700 mg from dietary sources)
magnesium (450 mg)
daily low-impact exercises
I do not take DHA, K2, or melatonin. I do take several other supplements: https://strontiumforbones.blogspot.com/2020/07/my-current-supplements.html
9 comments:
Very interesting, especially concerning the melatonin. Thank you.
Maya,
You should also read:
https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
Melatonin has been used for years as a sleep aid, but there is little evidence for it as a bone supplement. The authors of MOTS named only two studies on melatonin:
Kotlarczyk MP, Lassila HC, O’Neil CK, D’Amico F, Enderby LT, Witt‐Enderby PA, Balk JL. Melatonin osteoporosis prevention study (MOPS): a randomized, double‐blind, placebo‐controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women. J Pineal Res. 2012; 52:414–26. doi: 10.1111/j.1600‐079X.2011.00956.x
Amstrup AK, Sikjaer T, Heickendorff L, Mosekilde L, Rejnmark L. Melatonin improves bone mineral density at the femoral neck in postmenopausal women with osteopenia: a randomized controlled trial. J Pineal Res. 2015; 59:221–29. doi:10.1111/jpi.12252
Hi BoneLady,
I run out of AOR Strontium Support II, I can't find any on Amazon and iherb. I contact directly with AOR, they said it will takes 2 months to ship the order. Would you please recommend some alternative brand?
Thank you.
Christine
Hi chopin/Christine,
Vitacost Strontium is very reasonably priced. Each capsule contains 340 mg strontium. Other ingredients are hydroxypropyl methylcellulose, microcrystalline cellulose, vegetable stearic acid, and vegetable magnesium stearate.
Pure Encapsulations is expensive, and each capsule has only 227 mg strontium. However, the only other ingredients are vegetarian capsule (cellulose and water), hypoallergenic plant fiber (cellulose), and ascorbyl palmitate.
I have never taken either one but have online friends who have. The only two brands I have used are Doctor's Best Strontium Bonemaker, which is no longer made, and AOR Strontium Support II.
I buy most of my supplements at www.vitacost.com.
Hi BoneLady,
Thank you so much for your prompt help. I'll look at vitacost.com.
Christine
I echo Christine's comment. AOR Strontium supply dried up late last month and AOR seems to be going through a difficult time. I placed an order with them two weeks ago and the item still has not shipped.
If you had to choose for yourself, would you take VitaCost or Nature's Life Strontium?
Let me know,
Bone disciple
@Unknown of Nov 20, 2020,
If I had to choose between Vitacost Strontium and Nature's Life Strontium, I would choose Vitacost. I have never bought anything from Nature's Life and do not know of anyone using the company's strontium. I buy most of my supplements at Vitacost, am currently using Vitacost chelated zinc, and have several online friends who take Vitacost strontium.
@Christine and Unknown of Nov 20, 2020,
The supplier iHerb.com will have AOR Strontium Support II, 120 capsules, available November 27, 2020, and you can have them notify you when it comes in.
Thank you BoneLady for the supply information from iHerb.com. I have received the order from vitacost, they shipped pretty fast. It's the first time I ordered vitacost's strontium, I'll see how it works.
Christine
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