Natto contains 20 to 40mcg of K1, NO MK-4, and 900 to 1200mcg of
MK-7,8,9.
This video shows you what it looks like and how to eat it.
Skeleton Pirate
Artist: LindaB
WELCOME TO STRONTIUM FOR BONES BLOG
Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.
Browse the posts and visit the link library of references.
Saturday, August 16, 2014
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Wandering Skeleton
Artist: Joel Hoekstra
Osteoporotic Bone
Source: www.mayoclinic.com
How Strontium Builds Bones
Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.
Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.
When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.
For More Information about Strontium
- A Dose-response Study With Strontium Malonate
- A Review of the latest insights into the mechanism of action of strontium in bone
- Antifracture Efficacy Over 10 Years With Strontium Ranelate
- Combination of Micronutrients for Bone (COMB) Study: Bone Density after Micronutrient Intervention
- Effect of bone strontium on BMD measurements
- Effects of SrR on Calcium Metabolism
- Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone mineral detection
- Influence of strontium on bone mineral density and bone mineral content measurements by dual X-ray absorptiometry
- Interpretation of BMD Scans in Patients Stopping Strontium
- Melatonin-micronutrients Osteopenia Treatment Study (MOTS)
- National Osteoporosis Foundation
- Osteoporosis And Bone Physiology
- P471 BENEFICIAL EFFECTS OF STRONTIUM RANELATE COMPARED TO ALENDRONATE ON TRABECULAR BONE SCORE IN POST MENOPAUSAL OSTEOPOROTIC WOMEN: A 2-YEAR STUDY
- Post-Marketing Assessment of the Safety of Strontium Ranelate
- PubMed Abstract On The SOTI Study
- PubMed Abstract On The TROPOS Study
- Strontium ranelate Aristo
- Strontium Ranelate For Spinal Osteoarthritis
- Strontium: Breakthrough Against Osteoporosis
- Summary Safety Review - Strontium
- Thirteen Key Diagnostic Tests
5 comments:
I see a lot of negative stuff about Mk-4 ... is there any legit reason for this? I am unable to tolerate anything fermented so natto or MK-7 as a supplement is no good for me. I have just started taking MK-4 but wondering if its a bad idea?
Any thoughts??
Lee Lee,
MK-4 has a 6-8 hour biological half-life. Researchers in Japan gave MK-4 to osteoporotic women in doses of 15 mg three times per day for a total of 45 mg daily. MK-4’s short half-life will necessarily result in fluctuating K2 serum levels. No data are available at lower doses.
Lara Pizzorno, co-author of “Your Bones,” recommends vitamin K2 as MK-7, along with vitamin K1. Vitamin K1 is found in abundance in green, leafy vegetables. However, I have read complaints from some people regarding sleeplessness when taking MK-7. Here is a quote from an article she wrote:
“The question then becomes, which supplemental form(s) of MK at what dosage would be best? We suggest somewhere in the range of 45 - 90 mcg K1 plus 100 - 200 mcg K2 as MK-7/day. The lower end of the dosage range is likely to be sufficient for apparently healthy individuals, particularly since MK-7 accumulates in tissues to provide a reserve, while those with conditions related to vitamin K insufficiency may require the higher dose to help promote reversal of pathology.”
http://www.lmreview.com/articles/view/Vitamin-K2-Essential-for-Prevention-of-Age-Associated-Chronic-Disease/#fn-153-9
I eat lots of vegetables and my multivitamin contains 80 mcg of vitamin K1. Part of the K1 can be converted into K2 MK-4 in the body. The extent to which this takes place depends very much on the type of tissue. I follow the literature on K2 but I do not take any form of it myself.
Big Bad Wolf,
Millions of people, especially the Japanese, love natto. Many others love smelly cheese. Natto has been compared to smelly cheese.
Thanks very much for the info :) I'm in a tricky situation ... I am 46, have Osteoporosis but also make kidney stones ... and I find taking calcium, D3 or Strontium all increase stone formation ... I was hoping K2 would be enough to stop stop stones forming ... but as I said previously I cannot tolerate anything fermented so MK-7 is out for me. I might have to just try use MK-4 three times a day then and see how that goes. Also I am unable to eat anything green because my body cannot process sulphur or folate properly and greens basically poison me ... so I guess a K1 supplement too then ... oh life is fun! LOL
Lee Lee,
The National Kidney Foundation has information on diet and kidney stones.
http://www.kidney.org/atoz/content/diet.cfm
I hope taking MK-4 three times per day works as you would like it to. I would love to hear back from you after you have used MK-4 for several months to hear how it is working for you.
Good luck.
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