Skeleton Pirate

Skeleton Pirate
Artist: LindaB

WELCOME TO STRONTIUM FOR BONES BLOG

Have you experienced negative, and even dangerous, side effects from Fosamax (alendronate), Boniva (ibandronate), Actonel (risedronate), Reclast (zoledronic acid), Prolia (denosumab), Forteo (teriparatide), Tymlos (abaloparatide), or other drugs prescribed for osteoporosis? If you have, then rest assured there is a safe, effective treatment for this condition. Strontium, primarily in the form of strontium citrate, is taken orally once a day.

Visitors to my blog can leave comments or ask questions and can remain anonymous, if they wish. Their comments are relayed to my g-mail inbox. Below each post, the number of comments for that post is cited and underlined because it is a link. By clicking on that link below any post, a window opens so that a visitor can leave a comment. Ideally, visitors leave comments on posts most relevant to their comments. All comments to my posts are moderated by me.

Browse the posts and visit the link library of references.






Blog Archive

Friday, September 13, 2013

Protein Believed to Cause Postmenopausal Osteoporosis

Researchers have identified a protein that likely causes osteoporosis in women after menopause. In experiments on mice, the research team from Tokyo’s Keio University School of Medicine and other institutions found that a decrease in the secretion of estrogen enhances the function of HIF1 alpha protein. Once the amount of estrogen secreted by the ovaries begins to decline around the time of menopause, HIF1 alpha protein in osteoclasts increases.

Normal mice after menopause showed decreased femoral bone density compared with premenopausal levels, but mice whose genes were manipulated so as not to produce the HIF1 alpha protein did not show a decline of femoral bone density even after menopause. Moreover, a substance to inhibit the function of the HIF1 alpha protein that was given to postmenopausal mice led to an increase of bone density compared with premenopausal levels. The discovery is expected to lead to the development of an effective medicine to prevent osteoporosis.

The study is to be published in the online edition of the Proceedings of the U.S. National Academy of Science.

 

 

Sunday, September 1, 2013

From Osteoporosis to Osteopenia with Strontium Citrate


After five and a half years of taking strontium citrate (680 mg strontium daily), I went from osteoporosis to osteopenia. I was probably at the osteopenia stage much earlier, but I waited four years between my previous DEXA scan, which showed improvement at all sites but still left me with osteoporosis, and this one. My density increased 34% in the lumbar spine and 55% in the left hip! These numbers are phenomenal! Even if up to 50% of the change in BMD were attributed to the effect of strontium, which has a higher atomic number than calcium and will affect DEXA measurements, the numbers would still be great. My BMD is now 0.871 g/cm2 at the spine from L1- L4 (T-score -1.6), 0.692 g/cm2 at the left femoral neck (-1.4 T-score), and 0.775 g/cm2 at the left total hip (-1.4 T-score). Osteopenia is defined as T-scores < -1.0 and -2.5.

Wandering Skeleton

Wandering Skeleton
Artist: Joel Hoekstra

Osteoporotic Bone

Osteoporotic Bone
Source: www.mayoclinic.com

How Strontium Builds Bones

Strontium is a mineral that tends to accumulate in bone. Studies have shown that oral doses of strontium are a safe and effective way to prevent and reverse osteoporosis. Doses of 680 mg per day appear to be optimal. See my "For More Information About Strontium" links section.

Osteoporosis is caused by changes in bone production. In healthy young bones there is a constant cycle of new bone growth and bone removal. With age, more bone is removed and less new bone is produced. The bones become less dense and thus more fragile.

Scientists believe that strontium works in two ways. It may stimulate the replication of pre-osteoblasts, leading to an increase in osteoblasts (cells that build bone). Strontium also directly inhibits the activity of osteoclasts (cells that break down bone). The result is stronger bones.

When taking strontium, be sure to take 1200 mg calcium, 1000 IU vitamin D3, and 500 mg magnesium daily. It is best to take strontium late at night on an empty stomach. Calcium and strontium may compete with each other for absorption if taken together.